He will ride alongside teammate Conor Cummins at the Vauxhall International North West 200 and Monster Energy Isle of Man TT on the CBR1000RR Fireblade SP, and the pair will also line up in the Supersport class on Honda machinery for Jackson Racing.
Twenty-one times TT winner McGuinness, whose 2014 challenge was thwarted by a wrist injury sustained during pre-season, has also signed up to contest the Endurance World Championship Superstock series for the privately owned Jackson Racing squad.
Morecambe rider McGuinness, whose last TT win came in June with his maiden triumph in the Zero race on the Mugen machine, has warned he is out to prove there is still ‘plenty of life in the old dog yet’.
“There’s no denying that 2014 was a tough year for me. It shook my confidence and held me back but I’m ready to put it all behind me and get back to the business of winning races,” he told Motorcycle News.
“I’ve said it before but the Honda team is like family to me and that support means everything,”.
The 42-year-old’s long association with the Padgetts Racing team ended amicably at the end of 2014.
“I can’t wait to get back on the bike and prove that there’s life in the old dog yet,” he added.
Despite nursing a broken scaphoid, McGuinness managed two top 10 finishes at the TT in the Superbike and Senior races last year and is the last rider to beat Michael Dunlop in the blue riband class on the Mountain Course in the Senior race in 2013.
He also remains the fastest rider ever over six laps of the legendary 37.73-mile circuit, averaging 128.943mph on his way to victory over Dunlop in their thrilling Senior duel.
Honda boss Neil Tuxworth told Motorcycle News: “We’re very happy to retain both John McGuinness and Conor Cummins for our 2015 road racing campaign. It goes without saying that our well-established relationship with John is proven to reap results.
“Last year was tough for him with his injury but he still got some good results. He’s very determined and we have every confidence that he’ll come back fighting. He is still very capable of winning races.”